Seroquel XR is a prescription medicine used to treat schizophrenia in adults.

Seroquel XR is a prescription medicine used to treat bipolar disorder in adults, including:

• manic episodes associated with bipolar disorder alone or with lithium or divalproex
• depressive episodes associated with bipolar disorder
• long-term treatment of bipolar I disorder with lithium or divalproex

Seroquel XR is a prescription medicine used to treat major depressive disorder as add-on treatment with antidepressant medicines when your doctor determines that one antidepressant alone is not enough to treat your depression.